Tff1 | trefoil factor 1

GeneMGI:88135Synonyms: PS2, Bcei

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating fructosamine level	1 supporting dataset	Tff1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.11x10^-7
increased lean body mass	1 supporting dataset	Tff1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.26x10^-5
decreased circulating total protein level	1 supporting dataset	Tff1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.05x10^-5
decreased circulating serum albumin level	1 supporting dataset	Tff1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.3x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tff1.

Associated images

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Histopathology

There is no histopathology data found for Tff1.

IMPC related publications

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External links

No external links available for Tff1.

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*Tff1^{tm1(EGFP/cre/ERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Tff1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tff1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Tff1^{tm2(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell

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