B2m | beta-2 microglobulin
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Integument Nervous system Mortality/aging
14 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
4Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues
| small superior vagus ganglion | 1 supporting dataset | B2mtm1b(EUCOMM)Wtsi | heterozygote | Early adult | N/A * | ||
| hydrometra | 1 supporting dataset | B2mtm1b(EUCOMM)Wtsi | heterozygote | Early adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | B2mtm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | B2mtm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| increased circulating phosphate level | 1 supporting dataset | B2mtm1b(EUCOMM)Wtsi | heterozygote | Early adult | 8.58x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | B2mtm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | B2mtm1b(EUCOMM)Wtsi | heterozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for B2m.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| B2mtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| B2mtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| B2mtm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| B2mtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |