Atp5f1a | ATP synthase F1 subunit alpha

GeneMGI:88115Synonyms: Atpm, D18Ertd206e, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Pigmentation Integument Growth/size/body region Hematopoietic system Behavior/neurological

15 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

decreased body weight3 supporting datasetsAtp5f1atm1a(EUCOMM)WtsiheterozygoteEarly adult1.6x10-12 
abnormal skin pigmentation1 supporting datasetAtp5f1atm1a(EUCOMM)WtsiheterozygoteEarly adult9.13x10-5 
decreased mean corpuscular hemoglobin1 supporting datasetAtp5f1atm1a(EUCOMM)WtsiheterozygoteEarly adult4.37x10-5 
thrombocytosis1 supporting datasetAtp5f1atm1a(EUCOMM)WtsiheterozygoteEarly adult9.17x10-6 
abnormal behavior1 supporting datasetAtp5f1atm1a(EUCOMM)WtsiheterozygoteEarly adult4.62x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atp5f1atm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Atp5f1atm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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