Ampd1 | adenosine monophosphate deaminase 1

GeneMGI:88015Synonyms: Ampd-1

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:41Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	3 supporting datasets	Ampd1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased neutrophil cell number	1 supporting dataset	Ampd1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.17x10^-5
increased mean platelet volume	1 supporting dataset	Ampd1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.76x10^-5
enlarged lymph nodes	2 supporting datasets	Ampd1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ampd1.

Associated images

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Histopathology

There is no histopathology data found for Ampd1.

IMPC related publications

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External links

No external links available for Ampd1.

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*Ampd1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ampd1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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