Alox15 | arachidonate 15-lipoxygenase

GeneMGI:87997Synonyms: Alox12l, 12-LO, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:146Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Alox15^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Alox15^{tm1b(KOMP)Mbp}	homozygote	Early adult	6.96x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Alox15.

Associated images

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Histopathology

There is no histopathology data found for Alox15.

IMPC related publications

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External links

No external links available for Alox15.

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*Alox15^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Alox15^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Alox15^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Alox15^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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