Aldob | aldolase B, fructose-bisphosphate

GeneMGI:87995Synonyms: Aldo-2, Aldo2

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Growth/size/body region Skeleton Cardiovascular system Mortality/aging

14 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

abnormal heart left ventricle morphology4 supporting datasetsAldobtm2b(EUCOMM)WtsihomozygoteEarly adult1.62x10-7 
preweaning lethality, incomplete penetrance3 supporting datasetsAldobtm2b(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased body length1 supporting datasetAldobtm2b(EUCOMM)WtsihomozygoteEarly adult4.08x10-5 
decreased bone mineral density1 supporting datasetAldobtm2b(EUCOMM)WtsihomozygoteEarly adult2.82x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aldobtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Aldobtm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Aldobtm2b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Aldobtm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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