Adrb2 | adrenergic receptor, beta 2

GeneMGI:87938Synonyms: Adrb-2, beta 2-AR, +3 more

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hearing/vestibular/ear Vision/eye Liver/biliary system Hematopoietic system Renal/urinary system

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal spleen morphology	1 supporting dataset	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	2 supporting datasets	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal auditory brainstem response	1 supporting dataset	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	2.88x10^-6
abnormal eye morphology	1 supporting dataset	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small liver	1 supporting dataset	Adrb2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adrb2.

Associated images

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Histopathology

There is no histopathology data found for Adrb2.

IMPC related publications

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External links

No external links available for Adrb2.

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*Adrb2^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse
*Adrb2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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