Cfd | complement factor D
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Endocrine/exocrine gland Limbs/digits/tail Skeleton Renal/urinary system
16 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small kidney | 1 supporting dataset | Cfdem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal adrenal gland morphology | 1 supporting dataset | Cfdem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small adrenal glands | 1 supporting dataset | Cfdem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal caudal vertebrae morphology | 1 supporting dataset | Cfdem1(IMPC)Mbp | homozygote | Early adult | 1.19x10-6 | ||
| abnormal kidney morphology | 1 supporting dataset | Cfdem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Cfd mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Cfd.
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