Cfd | complement factor D

GeneMGI:87931Synonyms: D component (adipsin) of complement, factor D, +2 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Endocrine/exocrine gland Limbs/digits/tail Skeleton Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small kidney	1 supporting dataset	Cfd^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal adrenal gland morphology	1 supporting dataset	Cfd^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small adrenal glands	1 supporting dataset	Cfd^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal caudal vertebrae morphology	1 supporting dataset	Cfd^em1(IMPC)Mbp	homozygote	Early adult	1.19x10^-6
abnormal kidney morphology	1 supporting dataset	Cfd^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cfd.

Associated images

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Histopathology

There is no histopathology data found for Cfd.

IMPC related publications

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External links

No external links available for Cfd.

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*Cfd^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Cfd^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	ES Cell

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