Adk | adenosine kinase

GeneMGI:87930Synonyms: 5033405D03Rik, AK, +1 more

Physiological systems

23 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Integument Growth/size/body region Respiratory system Hematopoietic system Behavior/neurological Skeleton Mortality/aging

14 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



enlarged thymus	1 supporting dataset	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased anxiety-related response	1 supporting dataset	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	5.36x10^-5
abnormal spleen morphology	1 supporting dataset	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged lung	1 supporting dataset	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased lung tissue damping	2 supporting datasets	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	2.58x10^-5
decreased locomotor activity	2 supporting datasets	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	3.03x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Adk^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	4.78x10^-11
abnormal spine curvature	1 supporting dataset	Adk^{em1(IMPC)Ccpcz}	heterozygote	Early adult	3.04x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Adk.

Associated images

Loading...

Histopathology

There is no histopathology data found for Adk.

IMPC related publications

Loading...

External links

No external links available for Adk.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Adk^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Adk^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Adk^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes