Acvr1 | activin A receptor, type 1
Physiological systems
22 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
20 No significant impact
2 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Acvr1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Acvr1tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| increased circulating total protein level | 1 supporting dataset | Acvr1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.45x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Acvr1tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * |
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External links
No external links available for Acvr1.
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| Acvr1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Acvr1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Acvr1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Acvr1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Acvr1tm27043(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |