Acta2 | actin alpha 2, smooth muscle, aorta

GeneMGI:87909Synonyms: SMAalpha, 0610041G09Rik, +4 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased basophil cell number2 supporting datasetsActa2em1(IMPC)HhomozygoteEarly adult5.82x10-6 
decreased lymphocyte cell number1 supporting datasetActa2em1(IMPC)HhomozygoteEarly adult6.42x10-5 
decreased heart weight1 supporting datasetActa2em1(IMPC)HhomozygoteEarly adult4.13x10-5 
decreased mean corpuscular volume1 supporting datasetActa2em1(IMPC)HhomozygoteEarly adult3.17x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Acta2em1(IMPC)HIndelmouse
Acta2tm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)es cell
Acta2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Acta2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Acta2tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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