Chrna2 | cholinergic receptor nicotinic alpha 2 subunit

GeneMGI:87886Synonyms: Acra-2, Acra2

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Integument Limbs/digits/tail Skeleton Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



thick skin	1 supporting dataset	Chrna2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Chrna2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Chrna2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Chrna2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal caudal vertebrae morphology	1 supporting dataset	Chrna2^em1(IMPC)Mbp	homozygote	Early adult	1.54x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Chrna2.

Associated images

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Histopathology

There is no histopathology data found for Chrna2.

IMPC related publications

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External links

No external links available for Chrna2.

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*Chrna2^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Chrna2^{tm208612(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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