Acp2 | acid phosphatase 2, lysosomal

GeneMGI:87882Synonyms: LAP, Acp-2

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Skeleton

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased hemoglobin content	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.8x10^-8
decreased T cell number	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.34x10^-8
increased B cell number	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.8x10^-6
abnormal bone mineralization	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.18x10^-6
abnormal bone structure	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.25x10^-6
abnormal behavior	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.06x10^-5
decreased CD4-positive, alpha-beta T cell number	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.8x10^-5
decreased erythrocyte cell number	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.23x10^-6
increased bone mineral content	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.29x10^-9
decreased CD8-positive, alpha-beta T cell number	1 supporting dataset	Acp2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.26x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Acp2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Acp2.

IMPC related publications

Loading...

External links

No external links available for Acp2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Acp2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Acp2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes