Ache | acetylcholinesterase

GeneMGI:87876

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



no spontaneous movement	1 supporting dataset	Ache^em1(IMPC)Mbp	heterozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Ache^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small heart	1 supporting dataset	Ache^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
no spontaneous movement	1 supporting dataset	Ache^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Ache^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
increased neutrophil cell number	1 supporting dataset	Ache^em1(IMPC)Mbp	heterozygote	Early adult	8.25x10^-7
hemorrhage	1 supporting dataset	Ache^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ache.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ache.

IMPC related publications

Loading...

External links

No external links available for Ache.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ache^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse

My Genes