a | nonagouti

GeneMGI:87853Synonyms: agouti signal protein, As, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Integument Vision/eye Behavior/neurological Renal/urinary system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal skin morphology	2 supporting datasets	a^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	a^em1(IMPC)Mbp	homozygote	Early adult	5.99x10^-5
abnormal kidney morphology	1 supporting dataset	a^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased vertical activity	1 supporting dataset	a^em1(IMPC)Mbp	homozygote	Early adult	4.99x10^-5
small kidney	1 supporting dataset	a^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	a^em1(IMPC)Mbp	homozygote	Early adult	6.35x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for a.

Associated images

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Histopathology

There is no histopathology data found for a.

IMPC related publications

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External links

No external links available for a.

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*a^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*a^{tm40206(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*a^{tm40206(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes