Ostf1 | osteoclast stimulating factor 1

GeneMGI:700012Synonyms: SH3P2, C78236, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetOstf1tm1b(EUCOMM)HmguhomozygoteEarly adult7.76x10-8 
persistence of hyaloid vascular system1 supporting datasetOstf1tm1b(EUCOMM)HmguhomozygoteEarly adult3.41x10-5 
abnormal retina vasculature morphology1 supporting datasetOstf1tm1b(EUCOMM)HmguhomozygoteEarly adult2.49x10-5 
increased startle reflex1 supporting datasetOstf1tm1b(EUCOMM)HmguhomozygoteEarly adult9.89x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ostf1tm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Ostf1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ostf1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Ostf1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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