Cpgi5563 | CpG island 5563

GeneMGI:5670665Synonyms: CGI5563

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Mortality/aging

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	N/A ^*
increased lean body mass	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	1.57x10^-7
increased circulating chloride level	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	2.51x10^-5
decreased circulating triglyceride level	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	7.46x10^-10
decreased circulating glucose level	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	4.47x10^-5
decreased circulating cholesterol level	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	6.44x10^-15
decreased fasting circulating glucose level	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	1.3x10^-6
decreased circulating glycerol level	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	1.54x10^-9
decreased circulating LDL cholesterol level	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	2.86x10^-7
increased circulating magnesium level	1 supporting dataset	Cpgi5563^{tm1.1(NCC)WCS}	homozygote	Early adult	5.46x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cpgi5563.

Associated images

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Histopathology

There is no histopathology data found for Cpgi5563.

IMPC related publications

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External links

No external links available for Cpgi5563.

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*Cpgi5563^tm1(NCC)WCS*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Cpgi5563^tm1(NCC)WCS*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Cpgi5563^{tm1.1(NCC)WCS}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Cpgi5563^{tm1000451(L1L2_lncRNA_xpA3_BactNeo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Cpgi5563^{tm1000462(L1L2_lncRNA_xpA3_BactNeo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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