Ly6l | lymphocyte antigen 6 family member L

GeneMGI:5313101Synonyms: Gm20654

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Nervous system Vision/eye Mortality/aging Cardiovascular system

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina blood vessel morphology2 supporting datasetsLy6lem1(IMPC)TcpheterozygoteEarly adult6.66x10-6 
preweaning lethality, complete penetrance3 supporting datasetsLy6lem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal retina vasculature morphology1 supporting datasetLy6lem1(IMPC)TcpheterozygoteEarly adult7.68x10-6 
embryonic lethality prior to organogenesis1 supporting datasetLy6lem1(IMPC)TcphomozygoteE9.5N/A * 
abnormal eye morphology1 supporting datasetLy6lem1(IMPC)TcpheterozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetLy6lem1(IMPC)TcpheterozygoteEarly adult5.11x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ly6lem1(IMPC)TcpInter-exon deletionmouse

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