Xaf1 | XIAP associated factor 1

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Integument Digestive/alimentary Limbs/digits/tail Skeleton

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetXaf1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal stomach morphology1 supporting datasetXaf1em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged stomach1 supporting datasetXaf1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal caudal vertebrae morphology1 supporting datasetXaf1em1(IMPC)MbphomozygoteEarly adult1.19x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Xaf1em1(IMPC)MbpExon Deletionmouse
Xaf1tm38005(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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