Cyp3a59 | cytochrome P450, family 3, subfamily a, polypeptide 59

GeneMGI:3769707

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



thrombocytopenia	1 supporting dataset	Cyp3a59^{em1(IMPC)Marc}	heterozygote	Early adult	4.62x10^-8
decreased mean platelet volume	1 supporting dataset	Cyp3a59^{em1(IMPC)Marc}	heterozygote	Early adult	2.34x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Cyp3a59^{em1(IMPC)Marc}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cyp3a59.

Associated images

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Histopathology

There is no histopathology data found for Cyp3a59.

IMPC related publications

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External links

No external links available for Cyp3a59.

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*Cyp3a59^{em1(IMPC)Marc}*	Indel	‌	mouse
*Cyp3a59^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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