Rnaset2b | ribonuclease T2B

GeneMGI:3702087

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Renal/urinary system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



enlarged kidney	1 supporting dataset	Rnaset2b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Rnaset2b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased grip strength	2 supporting datasets	Rnaset2b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.03x10^-6
impaired glucose tolerance	1 supporting dataset	Rnaset2b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.88x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnaset2b.

Associated images

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Histopathology

There is no histopathology data found for Rnaset2b.

IMPC related publications

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External links

No external links available for Rnaset2b.

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*Rnaset2b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rnaset2b^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes