Alkal2 | ALK and LTK ligand 2

GeneMGI:3697448Synonyms: Fam150b, Augalpha, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Integument Vision/eye Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetAlkal2em1(IMPC)JheterozygoteEarly adult6.18x10-5 
exophthalmos1 supporting datasetAlkal2em1(IMPC)JhomozygoteEarly adult3.89x10-5 
cornea opacity1 supporting datasetAlkal2em1(IMPC)JhomozygoteEarly adult1.73x10-5 
narrow eye opening1 supporting datasetAlkal2em1(IMPC)JhomozygoteEarly adult1.16x10-5 
decreased grip strength2 supporting datasetsAlkal2em1(IMPC)JheterozygoteEarly adult2.43x10-6 
increased bone mineral content1 supporting datasetAlkal2em1(IMPC)JhomozygoteEarly adult4.53x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Alkal2em1(IMPC)JExon Deletionmouse
Alkal2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Alkal2tm419188(Ifitm2_intron_L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter