Fancf | Fanconi anemia, complementation group F
GeneMGI:3689889
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Vision/eye Hematopoietic system Cardiovascular system
14 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean corpuscular volume | 1 supporting dataset | Fancfem1(IMPC)J | homozygote | Early adult | 9.18x10-5 | ||
| cornea vascularization | 1 supporting dataset | Fancfem1(IMPC)J | homozygote | Early adult | 8.02x10-5 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Fancfem1(IMPC)J | homozygote | Early adult | 5.26x10-5 | ||
| cornea opacity | 1 supporting dataset | Fancfem1(IMPC)J | homozygote | Early adult | 2.89x10-5 | ||
| sclerocornea | 1 supporting dataset | Fancfem1(IMPC)J | homozygote | Early adult | 8.39x10-5 |
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Human diseases caused by Fancf mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Fancf.
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| Fancfem1(IMPC)J | Whole-gene deletion | | mouse |