Trabd2b | TraB domain containing 2B

GeneMGI:3650152Synonyms: Gm12824, Hkat

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Hematopoietic system Skeleton Cardiovascular system Craniofacial

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vertebral arch morphology	3 supporting datasets	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	2.09x10^-11
enlarged thymus	2 supporting datasets	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal vertebrae morphology	1 supporting dataset	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	7.17x10^-16
abnormal thymus morphology	2 supporting datasets	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
hydrocephaly	1 supporting dataset	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal head morphology	1 supporting dataset	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	7.32x10^-11
abnormal brain morphology	1 supporting dataset	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged adrenal glands	1 supporting dataset	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal snout morphology	1 supporting dataset	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	1.32x10^-11
abnormal cranium morphology	1 supporting dataset	Trabd2b^{em2(IMPC)Ccpcz}	homozygote	Early adult	3.81x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trabd2b.

Associated images

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Histopathology

There is no histopathology data found for Trabd2b.

IMPC related publications

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External links

No external links available for Trabd2b.

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*Trabd2b^{em2(IMPC)Ccpcz}*	Indel	‌	mouse
*Trabd2b^{tm99198(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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