Defb43 | defensin beta 43

GeneMGI:3647180Synonyms: EG654458

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hearing/vestibular/ear Cardiovascular system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	1 supporting dataset	Defb43^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.75x10^-5
thin ventricular wall	1 supporting dataset	Defb43^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.12x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Defb43.

Associated images

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Histopathology

There is no histopathology data found for Defb43.

IMPC related publications

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External links

No external links available for Defb43.

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*Defb43^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Defb43^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Defb43^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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