Tmem170b | transmembrane protein 170B

GeneMGI:3647046Synonyms: EG621976

Physiological systems

16 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

15 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:1Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance3 supporting datasetsTmem170bem1(IMPC)KmpchomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

Human diseases caused by Tmem170b mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Tmem170btm444529(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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