H2ab3 | H2A.B variant histone 3

GeneMGI:3644875Synonyms: H2afb3-ps, H2afb3, +2 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating total protein level1 supporting datasetH2ab3em1(IMPC)WtsihomozygoteEarly adult7.46x10-5 
decreased circulating serum albumin level1 supporting datasetH2ab3em1(IMPC)WtsihomozygoteEarly adult2.44x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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H2ab3em1(IMPC)WtsiDeletionmouse
H2ab3tm469645(Ifitm2_intron_L1L2_GT2_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
H2ab3tm469663(Ifitm2_intron_L1L2_GT2_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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