Otud6a | OTU domain containing 6A

GeneMGI:3644685Synonyms: EG408193

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased eosinophil cell number2 supporting datasetsOtud6atm1(KOMP)VlcghomozygoteEarly adult1.05x10-11 
increased circulating cholesterol level1 supporting datasetOtud6atm1(KOMP)VlcghomozygoteEarly adult1.37x10-5 
increased basophil cell number2 supporting datasetsOtud6atm1(KOMP)VlcghomozygoteEarly adult3.37x10-28 
hyperactivity2 supporting datasetsOtud6atm1(KOMP)VlcghomozygoteEarly adult6.56x10-8 
increased circulating HDL cholesterol level1 supporting datasetOtud6atm1(KOMP)VlcghomozygoteEarly adult1.75x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Otud6atm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse

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