Gnptab | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Physiological systems
22 / 24 physiological systems tested
13 Significantly impacted by the knock-out
Reproductive system Immune system Integument Endocrine/exocrine gland Embryo Growth/size/body region Digestive/alimentary Vision/eye Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system Renal/urinary system
9 No significant impact
2 Not tested
Data collections
Gene metrics:24Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged spleen | 2 supporting datasets | Gnptabem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| cataract | 1 supporting dataset | Gnptabem1(IMPC)Mbp | heterozygote | Early adult | 6.35x10-5 | ||
| abnormal skin morphology | 2 supporting datasets | Gnptabem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal stomach morphology | 1 supporting dataset | Gnptabem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Gnptabem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal ovary morphology | 1 supporting dataset | Gnptabem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal lymph node morphology | 2 supporting datasets | Gnptabem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| enlarged ovary | 1 supporting dataset | Gnptabem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal spleen morphology | 2 supporting datasets | Gnptabem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Gnptabem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Gnptab mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Gnptab.
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| Gnptabem1(IMPC)Mbp | Exon Deletion | | mouse |
| Gnptabtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |