Mir96 | microRNA 96

GeneMGI:3619440Synonyms: Mirn96, mmu-mir-96, +1 more

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Skeleton

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



impaired righting response	1 supporting dataset	Mir96^{tm3.2(IMPC)Wtsi}	homozygote	Early adult	8.76x10^-21
abnormal gait	1 supporting dataset	Mir96^Dmdo	homozygote	Early adult	1.18x10^-5
abnormal startle reflex	1 supporting dataset	Mir96^Dmdo	heterozygote	Early adult	1.27x10^-7
abnormal auditory brainstem response	6 supporting datasets	Mir96^{tm2.2(IMPC)Wtsi}	homozygote	Early adult	1.81x10^-9
abnormal cornea morphology	1 supporting dataset	Mir96^Dmdo	homozygote	Early adult	3.26x10^-5
increased leukocyte cell number	1 supporting dataset	Mir96^{tm2.2(IMPC)Wtsi}	heterozygote	Early adult	7.6x10^-5
abnormal behavior	2 supporting datasets	Mir96^Dmdo	homozygote	Early adult	4.71x10^-6
abnormal auditory brainstem response	5 supporting datasets	Mir96^{tm3.2(IMPC)Wtsi}	homozygote	Early adult	6.97x10^-8
trunk curl	1 supporting dataset	Mir96^{tm2.2(IMPC)Wtsi}	homozygote	Early adult	1.86x10^-15
trunk curl	1 supporting dataset	Mir96^Dmdo	homozygote	Early adult	4.91x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mir96.

Associated images

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Histopathology

There is no histopathology data found for Mir96.

IMPC related publications

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External links

No external links available for Mir96.

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*Mir96^{tm1(mirKO)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Mir96^{tm2(IMPC)Wtsi}*	Point mutation of nucleotide 28G->A, at location 13 of the seed region, (with selection cassette)	‌	es cell mouse
*Mir96^{tm2.2(IMPC)Wtsi}*	Point mutation of nucleotide 28G->A, at location 13 of the seed region, (post Flp, with no reporter and selection cassette)	‌	mouse
*Mir96^{tm3(IMPC)Wtsi}*	Point mutation of nucleotide 29C->A (with selection cassette)	‌	es cell mouse
*Mir96^{tm3.2(IMPC)Wtsi}*	Point mutation of nucleotide 29C->A (post Flp, with no reporter and selection cassette)	‌	mouse

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