Fam163a | family with sequence similarity 163, member A

GeneMGI:3618859Synonyms: A230106N23Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Vision/eye Hematopoietic system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased lean body mass	1 supporting dataset	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	8.43x10^-7
increased erythrocyte cell number	2 supporting datasets	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	6.53x10^-9
increased circulating total protein level	1 supporting dataset	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	2.95x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	5.07x10^-5
increased hemoglobin content	2 supporting datasets	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	2.68x10^-8
decreased total body fat amount	1 supporting dataset	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	3.53x10^-6
increased leukocyte cell number	1 supporting dataset	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	1.64x10^-8
increased hematocrit	2 supporting datasets	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	1.73x10^-8
improved glucose tolerance	1 supporting dataset	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	2.08x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Fam163a^{tm2b(KOMP)Wtsi}	homozygote	Early adult	1.7x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fam163a.

Associated images

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Histopathology

There is no histopathology data found for Fam163a.

IMPC related publications

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External links

No external links available for Fam163a.

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*Fam163a^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fam163a^{tm2b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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