Klhl32 | kelch-like 32

GeneMGI:3612790Synonyms: D4Ertd389e, LOC384000, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation1 supporting datasetKlhl32em1(IMPC)JhomozygoteEarly adult2.35x10-6 
improved glucose tolerance2 supporting datasetsKlhl32em1(IMPC)JhomozygoteEarly adult1.63x10-13 
decreased fasting circulating glucose level1 supporting datasetKlhl32em1(IMPC)JhomozygoteEarly adult8.49x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Klhl32em1(IMPC)JExon Deletionmouse
Klhl32tm193(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Klhl32tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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