Tox2 | TOX high mobility group box family member 2

GeneMGI:3611233Synonyms: LOC269389, RxHMG1

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Adipose tissue Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity2 supporting datasetsTox2em1(IMPC)HhomozygoteEarly adult5.05x10-5 
short tibia1 supporting datasetTox2em1(IMPC)HhomozygoteEarly adult2.87x10-7 
increased total body fat amount2 supporting datasetsTox2em1(IMPC)HhomozygoteEarly adult1.43x10-5 
abnormal gait1 supporting datasetTox2em1(IMPC)HhomozygoteEarly adult6.22x10-6 
decreased mean platelet volume1 supporting datasetTox2em1(IMPC)HhomozygoteEarly adult1.23x10-7 
decreased exploration in new environment1 supporting datasetTox2em1(IMPC)HhomozygoteEarly adult2.47x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Tox2em1(IMPC)HIndelmouse
Tox2em2(IMPC)HIndelmouse
Tox2tm55682(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter