Elfn2 | leucine rich repeat and fibronectin type III, extracellular 2

GeneMGI:3608416Synonyms: Lrrc62

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological Renal/urinary system

17 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsElfn2tm1.1(KOMP)VlcghomozygoteEarly adult7.62x10-22 
hyperactivity1 supporting datasetElfn2tm1.1(KOMP)VlcghomozygoteEarly adult1.8x10-15 
abnormal behavior2 supporting datasetsElfn2tm1.1(KOMP)VlcghomozygoteEarly adult7.62x10-22 
increased eosinophil cell number1 supporting datasetElfn2tm1.1(KOMP)VlcghomozygoteEarly adult1.74x10-5 
increased vertical activity1 supporting datasetElfn2tm1.1(KOMP)VlcghomozygoteEarly adult6.97x10-11 
abnormal vocalization1 supporting datasetElfn2tm1.1(KOMP)VlcghomozygoteEarly adult2.53x10-10 
abnormal kidney morphology1 supporting datasetElfn2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Elfn2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Elfn2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Elfn2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Elfn2tm403059(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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