Rft1 | RFT1 homolog

GeneMGI:3607791

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Limbs/digits/tail Hematopoietic system Skeleton Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

21Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased lymphocyte cell number	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	9.52x10^-5
increased mean corpuscular volume	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	7.39x10^-11
increased basophil cell number	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2x10^-5
increased monocyte cell number	2 supporting datasets	Rft1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.31x10^-6
decreased erythrocyte cell number	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.17x10^-5
increased hemoglobin content	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.27x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
increased mean corpuscular hemoglobin	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.94x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Rft1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Rft1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Rft1.

IMPC related publications

Loading...

External links

No external links available for Rft1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Rft1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rft1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rft1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Rft1^{tm43517(L1L2_st2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes