Shisa7 | shisa family member 7
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Vision/eye Behavior/neurological
13 No significant impact
7 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| tremors | 1 supporting dataset | Shisa7em1(IMPC)J | homozygote | Early adult | 3.01x10-14 | ||
| increased exploration in new environment | 1 supporting dataset | Shisa7em1(IMPC)J | homozygote | Early adult | 3.15x10-9 | ||
| hyperactivity | 8 supporting datasets | Shisa7em1(IMPC)J | homozygote | Early adult | 8.11x10-14 | ||
| decreased total body fat amount | 1 supporting dataset | Shisa7em1(IMPC)J | homozygote | Early adult | 5.11x10-6 | ||
| increased vertical activity | 1 supporting dataset | Shisa7em1(IMPC)J | homozygote | Early adult | 9.8x10-6 | ||
| cataract | 1 supporting dataset | Shisa7em1(IMPC)J | homozygote | Early adult | 6.54x10-6 | ||
| increased lean body mass | 2 supporting datasets | Shisa7em1(IMPC)J | homozygote | Early adult | 5.5x10-6 |
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Human diseases caused by Shisa7 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Shisa7.
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| Shisa7em1(IMPC)J | Exon Deletion | | mouse |
| Shisa7tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Shisa7tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |