Adgb | androglobin
Physiological systems
23 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Reproductive system Immune system Muscle Nervous system Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system
15 No significant impact
1 Not tested
Data collections
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| no spontaneous movement | 1 supporting dataset | Adgbem1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| increased eosinophil cell number | 1 supporting dataset | Adgbem1(IMPC)Mbp | heterozygote | Early adult | 1.89x10-6 | ||
| increased skeletal muscle mass | 1 supporting dataset | Adgbem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Adgbem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| increased freezing behavior | 1 supporting dataset | Adgbem1(IMPC)Mbp | heterozygote | Early adult | 2.37x10-5 | ||
| abnormal kidney morphology | 1 supporting dataset | Adgbem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| hydrocephaly | 1 supporting dataset | Adgbem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Adgbem1(IMPC)Mbp | homozygote | E18.5 | N/A * | ||
| male infertility | 1 supporting dataset | Adgbem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal brain morphology | 1 supporting dataset | Adgbem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Adgb mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Adgb.
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| Adgbem1(IMPC)Mbp | Exon Deletion | | mouse |
| Adgbtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Adgbtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |