Fbxw25 | F-box and WD-40 domain protein 25

GeneMGI:3588266Synonyms: E330001B16Rik

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Hematopoietic system Cardiovascular system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal digit morphology1 supporting datasetFbxw25em1(IMPC)CcpczhomozygoteEarly adult2.83x10-6 
abnormal heart morphology1 supporting datasetFbxw25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetFbxw25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetFbxw25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetFbxw25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fbxw25em1(IMPC)CcpczExon Deletionmouse

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