Slc51b | solute carrier family 51, beta subunit
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton
13 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged spleen | 1 supporting dataset | Slc51bem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased red blood cell distribution width | 1 supporting dataset | Slc51bem1(IMPC)Mbp | homozygote | Early adult | 4.27x10-12 | ||
| increased lean body mass | 1 supporting dataset | Slc51bem1(IMPC)Mbp | homozygote | Early adult | 7.76x10-10 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Slc51bem1(IMPC)Mbp | homozygote | Early adult | 6.96x10-5 | ||
| hydrometra | 1 supporting dataset | Slc51bem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal bone structure | 1 supporting dataset | Slc51bem1(IMPC)Mbp | homozygote | Early adult | 3.11x10-5 | ||
| abnormal spleen morphology | 1 supporting dataset | Slc51bem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased total body fat amount | 1 supporting dataset | Slc51bem1(IMPC)Mbp | homozygote | Early adult | 1.18x10-9 |
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Human diseases caused by Slc51b mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Slc51b.
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| Slc51bem1(IMPC)Mbp | Exon Deletion | | mouse |
| Slc51btm251897(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |