Slc51b | solute carrier family 51, beta subunit

GeneMGI:3582052Synonyms: Ostb

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton

13 No significant impact

4 Not tested

Gene metrics:10Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetSlc51bem1(IMPC)MbphomozygoteEarly adultN/A * 
increased red blood cell distribution width1 supporting datasetSlc51bem1(IMPC)MbphomozygoteEarly adult4.27x10-12 
increased lean body mass1 supporting datasetSlc51bem1(IMPC)MbphomozygoteEarly adult7.76x10-10 
increased circulating alkaline phosphatase level1 supporting datasetSlc51bem1(IMPC)MbphomozygoteEarly adult6.96x10-5 
hydrometra1 supporting datasetSlc51bem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal bone structure1 supporting datasetSlc51bem1(IMPC)MbphomozygoteEarly adult3.11x10-5 
abnormal spleen morphology1 supporting datasetSlc51bem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased total body fat amount1 supporting datasetSlc51bem1(IMPC)MbphomozygoteEarly adult1.18x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc51bem1(IMPC)MbpExon Deletionmouse
Slc51btm251897(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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