Lemd3 | LEM domain containing 3
Physiological systems
13 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging
11 No significant impact
11 Not tested
Data collections
Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased thigmotaxis | 2 supporting datasets | Lemd3em1(IMPC)Bay | heterozygote | Early adult | 2.16x10-6 | ||
| preweaning lethality, complete penetrance | 2 supporting datasets | Lemd3em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| hyperactivity | 2 supporting datasets | Lemd3em1(IMPC)Bay | heterozygote | Early adult | 1.22x10-5 | ||
| abnormal behavior | 1 supporting dataset | Lemd3em1(IMPC)Bay | heterozygote | Early adult | 2.16x10-6 | ||
| decreased anxiety-related response | 1 supporting dataset | Lemd3em1(IMPC)Bay | heterozygote | Early adult | 5.67x10-5 | ||
| decreased locomotor activity | 1 supporting dataset | Lemd3em1(IMPC)Bay | heterozygote | Early adult | 1.16x10-6 |
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External links
No external links available for Lemd3.
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| Lemd3em1(IMPC)Bay | Exon Deletion | | mouse |
| Lemd3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Lemd3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |