Fcho2 | FCH domain only 2

GeneMGI:3505790Synonyms: 5832424M12Rik

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Mortality/aging

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin1 supporting datasetFcho2tm1b(EUCOMM)HmguheterozygoteEarly adult9.83x10-5 
preweaning lethality, complete penetrance1 supporting datasetFcho2tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased red blood cell distribution width1 supporting datasetFcho2tm1b(EUCOMM)HmguheterozygoteEarly adult1.83x10-7 
decreased circulating fructosamine level1 supporting datasetFcho2tm1b(EUCOMM)HmguheterozygoteEarly adult1.31x10-5 
decreased circulating serum albumin level1 supporting datasetFcho2tm1b(EUCOMM)HmguheterozygoteEarly adult6.93x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fcho2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fcho2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Fcho2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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