Dynlt4 | dynein light chain Tctex-type 4

GeneMGI:3045358Synonyms: Tctex1d4, 4833401D15Rik

Physiological systems

14 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Hematopoietic system

13 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased erythrocyte cell number1 supporting datasetDynlt4tm1e(EUCOMM)WtsihomozygoteEarly adult1.43x10-7 
decreased hemoglobin content1 supporting datasetDynlt4tm1e(EUCOMM)WtsihomozygoteEarly adult7.84x10-8 
decreased hematocrit1 supporting datasetDynlt4tm1e(EUCOMM)WtsihomozygoteEarly adult3.25x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dynlt4tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Dynlt4tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
mouse

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