Slc17a8 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

GeneMGI:3039629Synonyms: Vgt3, Vglut3

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Digestive/alimentary Nervous system Vision/eye Hearing/vestibular/ear Behavior/neurological Renal/urinary system

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	6 supporting datasets	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	1.83x10^-6
abnormal eye morphology	1 supporting dataset	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	7 supporting datasets	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	4.44x10^-57
abnormal adrenal gland morphology	1 supporting dataset	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	1.88x10^-5
abnormal lymph node morphology	1 supporting dataset	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal colon morphology	1 supporting dataset	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased startle reflex	1 supporting dataset	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	1.13x10^-13
abnormal startle reflex	1 supporting dataset	Slc17a8^em1(IMPC)Mbp	homozygote	Early adult	1.15x10^-18

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc17a8.

Associated images

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Histopathology

There is no histopathology data found for Slc17a8.

IMPC related publications

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External links

No external links available for Slc17a8.

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*Slc17a8^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Slc17a8^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Slc17a8^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Slc17a8^{tm42931(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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