Rsad1 | radical S-adenosyl methionine domain containing 1

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Mortality/aging

13 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:41Adult tissues
0Embryo tissues

Phenotypes

decreased blood urea nitrogen level1 supporting datasetRsad1tm1.1(KOMP)VlcgheterozygoteEarly adult6.48x10-7 
small thymus1 supporting datasetRsad1tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
small adrenal glands1 supporting datasetRsad1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsRsad1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal uterus morphology1 supporting datasetRsad1tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetRsad1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
enlarged lymph nodes2 supporting datasetsRsad1tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rsad1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Rsad1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Rsad1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rsad1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Rsad1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rsad1tm3a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rsad1tm3e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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