Fads6 | fatty acid desaturase domain family, member 6

GeneMGI:3039592Synonyms: OTTMUSG00000021749, BC050213

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Integument Digestive/alimentary Vision/eye Cardiovascular system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating potassium level	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.92x10^-10
abnormal retina blood vessel morphology	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.85x10^-7
abnormal retina vasculature morphology	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.93x10^-6
increased circulating creatinine level	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.01x10^-7
abnormal retina morphology	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.92x10^-10
abnormal skin morphology	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.33x10^-6
persistence of hyaloid vascular system	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.02x10^-15
abnormal duodenum morphology	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal cecum morphology	1 supporting dataset	Fads6^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fads6.

Associated images

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Histopathology

There is no histopathology data found for Fads6.

IMPC related publications

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External links

No external links available for Fads6.

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*Fads6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Fads6^{tm147(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Fads6^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fads6^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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