Macroh2a2 | macroH2A.2 histone
Physiological systems
20 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Renal/urinary system
12 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged lymph nodes | 2 supporting datasets | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | N/A * | ||
| decreased locomotor activity | 1 supporting dataset | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | 2.68x10-5 | ||
| decreased circulating iron level | 1 supporting dataset | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | 4.24x10-5 | ||
| abnormal kidney morphology | 1 supporting dataset | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | N/A * | ||
| increased grip strength | 2 supporting datasets | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | 5.85x10-11 | ||
| enlarged spleen | 1 supporting dataset | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | N/A * | ||
| decreased liver weight | 1 supporting dataset | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | 1.43x10-5 | ||
| abnormal thymus morphology | 1 supporting dataset | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | N/A * | ||
| abnormal liver morphology | 2 supporting datasets | Macroh2a2em1(IMPC)Hmgu | homozygote | Late adult | N/A * |
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External links
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| Macroh2a2em1(IMPC)Hmgu | Exon Deletion | | mouse |
| Macroh2a2tm79392(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |