Zfp281 | zinc finger protein 281

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased thigmotaxis	2 supporting datasets	Zfp281^em1(IMPC)Mbp	heterozygote	Early adult	2.61x10^-5
hyperactivity	1 supporting dataset	Zfp281^em1(IMPC)Mbp	heterozygote	Early adult	9.37x10^-5
decreased anxiety-related response	1 supporting dataset	Zfp281^em1(IMPC)Mbp	heterozygote	Early adult	8.09x10^-5
abnormal behavior	1 supporting dataset	Zfp281^em1(IMPC)Mbp	heterozygote	Early adult	3.37x10^-5
small spleen	1 supporting dataset	Zfp281^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
increased circulating alkaline phosphatase level	1 supporting dataset	Zfp281^em1(IMPC)Mbp	heterozygote	Early adult	1.21x10^-6
abnormal spleen morphology	1 supporting dataset	Zfp281^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Zfp281^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Zfp281^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Zfp281^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Zfp281.

Associated images

Loading...

Histopathology

There is no histopathology data found for Zfp281.

IMPC related publications

Loading...

External links

No external links available for Zfp281.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Zfp281^em1(IMPC)Mbp*	Intra-exon deletion	‌	mouse
*Zfp281^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Zfp281^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes