Zfp281 | zinc finger protein 281
GeneMGI:3029290
Physiological systems
21 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system
14 No significant impact
3 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased thigmotaxis | 2 supporting datasets | Zfp281em1(IMPC)Mbp | heterozygote | Early adult | 2.61x10-5 | ||
| hyperactivity | 1 supporting dataset | Zfp281em1(IMPC)Mbp | heterozygote | Early adult | 9.37x10-5 | ||
| decreased anxiety-related response | 1 supporting dataset | Zfp281em1(IMPC)Mbp | heterozygote | Early adult | 8.09x10-5 | ||
| abnormal behavior | 1 supporting dataset | Zfp281em1(IMPC)Mbp | heterozygote | Early adult | 3.37x10-5 | ||
| small spleen | 1 supporting dataset | Zfp281em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Zfp281em1(IMPC)Mbp | heterozygote | Early adult | 1.21x10-6 | ||
| abnormal spleen morphology | 1 supporting dataset | Zfp281em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| enlarged kidney | 1 supporting dataset | Zfp281em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Zfp281em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Zfp281em1(IMPC)Mbp | homozygote | E9.5 | N/A * |
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This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Zfp281.
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| Zfp281em1(IMPC)Mbp | Intra-exon deletion | | mouse |
| Zfp281tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Zfp281tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |