Iqgap3 | IQ motif containing GTPase activating protein 3

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Mortality/aging Cardiovascular system

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance2 supporting datasetsIqgap3em1(IMPC)BayhomozygoteEarly adultN/A * 
increased heart rate1 supporting datasetIqgap3em1(IMPC)BayheterozygoteEarly adult3.85x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Iqgap3em1(IMPC)BayExon Deletionmouse
Iqgap3tm356848(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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