Rap1gap2 | RAP1 GTPase activating protein 2

GeneMGI:3028623Synonyms: Garnl4, LOC380710

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hearing/vestibular/ear Behavior/neurological Cardiovascular system

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased aggression	1 supporting dataset	Rap1gap2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.98x10^-6
abnormal auditory brainstem response	3 supporting datasets	Rap1gap2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.75x10^-9
hyperactivity	4 supporting datasets	Rap1gap2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.76x10^-10
increased circulating phosphate level	1 supporting dataset	Rap1gap2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.52x10^-5
increased heart weight	1 supporting dataset	Rap1gap2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.35x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rap1gap2.

Associated images

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Histopathology

There is no histopathology data found for Rap1gap2.

IMPC related publications

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External links

No external links available for Rap1gap2.

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*Rap1gap2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rap1gap2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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