Lrrc4b | leucine rich repeat containing 4B

GeneMGI:3027390Synonyms: Lrig4, NGL-3, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological Skeleton Mortality/aging

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetLrrc4bem1(IMPC)JhomozygoteEarly adultN/A * 
increased anxiety-related response1 supporting datasetLrrc4bem1(IMPC)JhomozygoteEarly adult2.65x10-7 
decreased grip strength2 supporting datasetsLrrc4bem1(IMPC)JhomozygoteEarly adult3.62x10-7 
increased vertical activity1 supporting datasetLrrc4bem1(IMPC)JhomozygoteEarly adult6.32x10-5 
decreased locomotor activity3 supporting datasetsLrrc4bem1(IMPC)JhomozygoteEarly adult3.79x10-6 
abnormal bone structure1 supporting datasetLrrc4bem1(IMPC)JhomozygoteEarly adult4.51x10-8 
increased hematocrit1 supporting datasetLrrc4bem1(IMPC)JhomozygoteEarly adult3.05x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lrrc4bem1(IMPC)JExon Deletionmouse

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